You are your pet’s first line of defense against fleas and ticks. With a little research into pest prevention, you can ensure your pet remains happy and pest-free.  

Don’t know which anti-flea medication to choose? We’ve laid out some of the benefits of a few leading brands, along with information on why certain medications might not be right for your dog. As always, if you’re not sure, reach out to your veterinarian with any questions.  

Credelio (lotilaner)

• Chewable tablet  

• Given orally every 30 days – best given with food  

• For dogs 8 weeks and older  

• To be used in dogs 4.4 lbs. or larger

• Starts to kill fleas & ticks in 4 hours

• Kills 98.7% of ticks in 8 hours 

• Not evaluated on breeding, pregnant, or lactating dogs 

• CAUTION WITH DOGS WITH A HISTORY OF SEIZURES 

Bravecto (fluralaner)

• Available in chewable tablets and topical solution  

• Given orally or applied topically every 12  weeks – best to give oral tablet with food

• To be used in dogs 6 months and older

• For dogs 4.4 lbs. or greater 

• Starts to kill fleas in 2 hours 

• Starts to kill ticks in 12 hours 

• Safe for breeding, pregnant, and lactating dogs 

• CAUTION WITH DOGS WITH A HISTORY OF SEIZURES  

Nexgard (afoxolaner)

• Chewable tablet 

• Give orally every 30 days 

• For dogs 8 weeks and older  

• To be used in dogs 4 lbs. or bigger 

• Starts to kill fleas in 4 hours – 100% effective  against fleas in 24 hours 

• Starts to kill ticks in 48-72 hours, depending on species 

• Not evaluated in breeding, pregnant, or lactating dogs 

• CAUTION WITH DOGS WITH A HISTORY OF SEIZURES

Vectra 3D

• ** Repellent** 

• Topical solution 

• Apply at the base of the neck every 30 days

• Remains after swimming and bathing

• For dogs 8 weeks and older 

• Fors dogs 5 lbs or heavier 

• Starts to kill pre-existing fleas in 6 hours

• Kills pre-existing ticks within 24-48 hours 

• Effective against fleas, ticks, mosquitos, mites, lice, and biting flies 

• Causes “hot foot” reaction to keep non-flying parasites  away from the skin  

• Kills new fleas and ticks on contact 

• 80% of mosquitos and other flying insects won’t land on the treated pet 

• Do not use with breeding, pregnant, or lactating dogs  

** Use caution when buying any flea and tick prevention from a source other than your veterinarian**